Here is version two of a precision pt100 frontend for temperature measurements between +22C and +42C. The circuit uses a 4-wire connection with a +/-500uA sensing-current. It outputs a +/-10V voltage centered around +32C by way of a 112 Ohm reference resistor. The voltage over the reference-resistor can be used to correct for drift in the sensing-current.
Compared to v1 I changed the current source to the "Improved Howland" design, and assembled the instrumentation amplifiers from zero-drift op-amps with very small input offset voltage and input bias current.
Note: The op-amp shown, AD8551/8552/8554, is a single-supply +5V op-amp and this circuit will not work as such (NI Multisim will happily simulate it though!). Use e.g. OP2177 or OPA2188 for bipolar operation at +/-12 V.